Sir Syed University of Engineering and Technology has been sponsored by Aligarh Muslim University Old Boys' Association of Pakistan, Karachi. It was set up through Sindh Government Ordinance No. XII of 1993 dated 6th October, 1993 and the Charter granted by Governor of Sindh on 8th October, 1993. The Act was passed by the provincial Assembly of Sindh on 17th September, 1995 and assented by Governor of Sindh on 16th October 1995, and published in the Gazette as "Sir Syed University of Engineering and Technology, Act 1995 - Sindh Act No. X of 1995."
The Association decided to establish a high class University of Engineering and Technology as a Centre of Excellence offering instructions of International Standard with integrated programmes dealing with the fast growing technologies of the world with courses designed to produce qualified personnel of high calibre specialising in new technologies needed in developing countries. This objective is in line with the Government policy of inducting the private sector for promoting Education in Engineering and Technical subjects at graduate and post-graduate levels.
In its first phase, the University has been established on a plot of 8 acres in Block-5 of Gulshan-e-Iqbal on Main University Road. For future expansion, a plot measuring 200 acres has been acquired on link road.